| Oligo 6.86 - OLIGO is a multi-functional
program that searches for and
selects oligonucleotides from
a sequence file for polymerase
chain reaction (PCR), DNA
sequencing, site-directed
mutagenesis, and various
hybridization applications. It
calculates hybridization
temperature and secondary
structure of oligonucleotides
based on the nearest neighbor
thermodynamic values. It is
also a good tool for
construction of synthetic
genes, finding an appropriate
sequencing primer among those
already synthesized, finding
and multiplexing consensus
prmers and probes, and even
finding potential restriction
sites in a protein.The OLIGO
software has been broadly
accepted as the industry
software standard for
selecting and analyzing
oligonucleotides for various
molecular biology
applications. The first
commercial version of the
software was introduced in
1989. |